The endpoint layer for peptide research.

Cryptographically attested theses. Biosecurity-gated synthesis. Real-world cohort outcomes pre-registered before the results exist. Verifiable in your browser, without a server. Peptide MD is the human-use endpoint layer that peptide research has been missing.

Preview data
Live cohortcohort-2026-q2-tendon-01
Primary endpoint

Goniometric ROM gain at week 6 vs. baseline

Participants
48/60
Cohort treasury
$185k
The endpoint and analysis plan committed on 2026-03-04. Results will be hash-revealed at cohort close - not before.

The cohort above is preview data so you can see the layout. Open your own pre-registered cohort with a real endpoint and a real participant set.

How OEA-V1 works

Pre-registration as a cryptographic primitive.

Watch a cohort host commit an endpoint and analysis plan to a 32-byte hash before recruitment opens. The reveal binds to that exact commitment at cohort close - anyone replays the chain in their browser. No retro-fitting. No editorial trust.

Readycohort-2026-q2-tendon-01
  1. 01 plan
    Host writes the analysis plan
  2. 02 jcs
    Canonicalize JSON (RFC 8785)
  3. 03 hash
    Compute SHA-256 over canonical bytes
  4. 04 commit
    Commit hash on-chain
  5. 05 run
    Cohort runs
  6. 06 reveal
    Reveal window opens
  7. 07 verified
    Anyone replays the chain
Analysis plan
-
Canonical bytes
(awaiting canonicalize step)
SHA-256 commit
0000000000000000000000000000000000000000000000000000000000000000
Cohort timeline
2026-03-042026-06-24
week 0 / 16 · 0 / 60 enrolled
Verifier verdict
Reveal pending. The pre-registration commitment is published; results cannot be backdated.
XTL

Extended Thesis Loop

Six-stage pipeline from signal intake to outcome reveal.

PDA

Peptide Design Attestation

Design-stage attestations sealed and verifiable in-browser.

OEA

Outcome Evidence Attestation

Cohort endpoints sealed before results exist.

BioGate

Public Biosecurity Tier

Profile-HMM screen with GREEN/AMBER/RED/BLACK.

Featured protocols

Curated, cited, and gated by jurisdiction.

All protocols →
Indexed peptides

Every entry carries its provenance.

All peptides →
Three layers, one stack

Outcomes, practitioner tools, and a living oracle.

Peptide MD is the human-use endpoint layer for peptide research: outcome attestations from real cohorts, jurisdiction-gated practitioner tooling, COA-backed supply, and outcome-conditioned posteriors. Every layer is cryptographically verifiable in the browser.

01

Outcomes Layer

Pre-registered endpoints, wearable-grade RWE, OEA cryptographic reveal. Real humans, real metrics, real timestamps.

02

Practitioner Tooling

Eight-audience protocol cards. Jurisdiction gates before order, GMP-verified COA per batch, side-effect reporting in-line with attestation.

03

Living Outcome Oracle

Beta posteriors per (peptide, indication, baseline biomarker, cohort). Updates every revealed OEA. Reputation as math, conditioned on outcomes.

Public verification surface

Verify any attestation in your browser.

The Peptide MD Verifier checks PDA-V1 design attestations and OEA-V1 reveal artifacts. It uses Web Crypto SubtleCrypto end-to-end. No server call. No telemetry.

$ npm i @peptide-md/verifier
import { verifyPDA, verifyOEA } from'@peptide-md/verifier'
const result = await verifyPDA(bundle)
{ passed: true, source: 'peptide-md',
grade: 'B', biogate: 'GREEN',
pda: '28dbab77f5…3a640e' }
Cross-language byte-identical determinism · verifier diff is published in ARCHITECTURE.md