Grade BRUOverifiedBioGate · GREEN

Dermal & Follicular Renewal

Photoaged skin, scalp follicle restoration in androgenic-alopecia early stage

ghk-cu ↗

Protocol card

Eight audiences, one source of truth.

For clinicians

Dose & cycle

GHK-Cu 1% topical bid + microneedling 1.5 mm weekly

Cycle

Continuous topical

Duration

16 weeks, photographic + trichoscopy at week 0 / 8 / 16

For patients

Monitoring endpoints

✓modified Hamilton-Norwood
✓trichoscopy follicular density
✓VISIA wrinkle score

Contraindications

✕copper allergy
✕active dermatitis at site

Jurisdiction gates

US ✓

Cosmetic, non-prescription

EU ✓

Cosmetic regulation 1223/2009

UK ✓

Cosmetic

AU ✓

Cosmetic

Constituent peptides

Provenance, attestations, and structures.

GHK-CuverifiedBioGate · GREEN

Structural preview · ESMFold-2 mockdeterministic per sequence

GHK

Tripeptide-copper complex; modulates gene expression in dermal fibroblasts and downregulates TGF-β scarring pathways.

IP economics

Cohort outcomes feed the royalty cascade.

Every revealed OEA from this protocol's cohorts updates the upstream IPNFT's outcome posterior. Holders receive pro-rata royalties from licensing, lab-fee escrow, and approved CRO contracts. Peptide MD does not custody the IPNFT; it indexes it through the Molecule registry.

IPNFT · Molecule IPNFT V2Solana

GHK-Cu

bb9aee…94c09a

Royalty cascade

8.07%

Holders

323

Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.

Supply provenance

COA-backed batches in the index.

Batch	Supplier	Purity (HPLC)	Endotoxin (EU/mg)	Manufactured	Hash
HP-GHK-2026-0228-B	Helix Pharma EU Netherlands (GMP Annex 1)	98.9%	0.18	2026-02-28

Citations

Every claim, traceable.

Grade A2018 · Int J Mol Sci

The Effect of the Human Peptide GHK on Gene Expression Relevant to Skin

Pickart L, Margolina A.

PMID 26371021