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Two peptides, one row at a time.

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Peptide A

Thymosin α1 (Zadaxin)

verifiedBioGate · GREENGrade B
chronic hepatitis B/C adjunct
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    SDAAVDTSSEITTKDLKEKKEVVEEAEN
    GEPPPGKPADDAGLV
  • Length≠
    28 aa
    15 aa
  • Molecular weight≠
    3108.31
    1419.55
  • Modifications≠
    acetylated N-terminus
    acetyl-N-terminus
  • Mechanism

    28-residue immunomodulatory peptide; promotes T-cell maturation via TLR signaling. Approved in 35+ countries (not FDA) for hepatitis indications.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    3
    4
Outcomes
  • RWE cohorts
    5
    5
  • Total participants≠
    516
    270
  • Primary endpoint Δ≠
    -0.62 Δ HRV ms (8-week)
    95% CI [-2.29, 1.06]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    32.0%
    β(24.9, 53.0)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    -
    10.04%
Indications
  • Listed indications≠
    • · chronic hepatitis B/C adjunct
    • · immune reconstitution
    • · vaccine adjuvant research
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing