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verifiedBioGate · GREENGrade B

Thymosin α1 (Zadaxin)

SDAAVDTSSEITTKDLKEKKEVVEEAEN

28-residue immunomodulatory peptide; promotes T-cell maturation via TLR signaling. Approved in 35+ countries (not FDA) for hepatitis indications.

acetylated N-terminus
MW
3108.31
Length
28aa
Posterior
32.0%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · acetylated N-terminus
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
3
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
5
Participants
516
Mean Δ
-0.62
Δ HRV ms (8-week) · 95% CI [-2.29, 1.06]
IPNFT - Not minted

This peptide is not currently represented as an IPNFT. Cohort outcomes feed back into the unminted pool.

Citations

Source literature.

Grade B2007 · Curr Opin Pharmacol

Thymosin alpha 1: a historical overview

Garaci E et al.

PMID 17683988