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Peptide A

Substance P

warningBioGate · AMBERGrade B
pain signaling research
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    RPKPQQFFGLM
    GEPPPGKPADDAGLV
  • Length≠
    11 aa
    15 aa
  • Molecular weight≠
    1347.63
    1419.55
  • Modifications≠
    amidated C-terminustachykinin family
    acetyl-N-terminus
  • Mechanism

    Undecapeptide tachykinin; primary NK1 receptor agonist driving nociception, vasodilation, and neurogenic inflammation. NK1 antagonists (aprepitant) approved for chemo-induced nausea.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate≠
    warningBioGate · AMBER
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    2
    4
Outcomes
  • RWE cohorts≠
    1
    5
  • Total participants≠
    76
    270
  • Primary endpoint Δ≠
    +5.56 Δ HRV ms (8-week)
    95% CI [4.1, 7.02]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    71.3%
    β(61.1, 24.6)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    -
    10.04%
Indications
  • Listed indications≠
    • · pain signaling research
    • · neurogenic inflammation
    • · depression studies
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing