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Peptide A

Secretin (ChiRhoStim)

verifiedBioGate · GREENGrade B
pancreatic function diagnostic
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    HSDGTFTSELSRLREGARLQRLLQGLV
    GEPPPGKPADDAGLV
  • Length≠
    27 aa
    15 aa
  • Molecular weight≠
    3039.50
    1419.55
  • Modifications≠
    amidated C-terminus27-residue duodenal S-cell hormone
    acetyl-N-terminus
  • Mechanism

    Duodenal S-cell secretagogue; activates pancreatic ductal SCT receptor to drive bicarbonate-rich fluid secretion. First hormone described (Bayliss & Starling, 1902).

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    6
    4
Outcomes
  • RWE cohorts
    5
    5
  • Total participants≠
    56
    270
  • Primary endpoint Δ≠
    +6.61 Δ HRV ms (8-week)
    95% CI [4.95, 8.26]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    38.3%
    β(47.4, 76.4)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    Molecule IPNFT V2
    Solana · 472 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    11.37%
    10.04%
Indications
  • Listed indications≠
    • · pancreatic function diagnostic
    • · ERCP-related diagnostics
    • · MRCP enhancement
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing