verifiedBioGate · GREENGrade B

Secretin (ChiRhoStim)

HSDGTFTSELSRLREGARLQRLLQGLV

Duodenal S-cell secretagogue; activates pancreatic ductal SCT receptor to drive bicarbonate-rich fluid secretion. First hormone described (Bayliss & Starling, 1902).

amidated C-terminus27-residue duodenal S-cell hormone

3039.50

Length

27aa

Posterior

38.3%

Structural preview · ESMFold-2 mockdeterministic per sequence

Backbone preview · amidated C-terminus

PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation

Protocol version: PDA-V1
Source: peptide-md
Model version: structure-fm-2026.04
Candidates emitted: 6
Signed: 2026-04-21T08:14:33Z

Verifiable in your browser at /verifier with @peptide-md/verifier.

Verify this attestation →Download dossier (PDF)Compare with…

Real-world evidence

Cohort-attested outcomes.

Cohorts

Participants

Mean Δ

+6.61

Δ HRV ms (8-week) · 95% CI [4.95, 8.26]

IPNFT · Molecule IPNFT V2Solana

Secretin (ChiRhoStim)

e9f1e9…f8e6f1

Royalty cascade

11.37%

Holders

472

Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.

Citations

Source literature.

Grade B2003 · J Gastroenterol

Secretin, 100 years later

Chey WY, Chang TM.

PMID 16718820