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Peptide A

KPV

verifiedBioGate · GREENGrade B
intestinal inflammation research
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    KPV
    GEPPPGKPADDAGLV
  • Length≠
    3 aa
    15 aa
  • Molecular weight≠
    412.52
    1419.55
  • Modifications≠
    α-MSH C-terminal tripeptide
    acetyl-N-terminus
  • Mechanism

    C-terminal tripeptide of α-MSH; downregulates NF-κB inflammatory cascade in epithelial cells via PepT1-mediated uptake.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    3
    4
Outcomes
  • RWE cohorts≠
    7
    5
  • Total participants≠
    219
    270
  • Primary endpoint Δ≠
    +1.71 Δ HRV ms (8-week)
    95% CI [0.38, 3.04]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    5.3%
    β(4.4, 78.3)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    -
    10.04%
Indications
  • Listed indications≠
    • · intestinal inflammation research
    • · topical wound healing
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing