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verifiedBioGate · GREENGrade B
KPV
KPVC-terminal tripeptide of α-MSH; downregulates NF-κB inflammatory cascade in epithelial cells via PepT1-mediated uptake.
α-MSH C-terminal tripeptide
MW
412.52
Length
3aa
Posterior
5.3%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · α-MSH C-terminal tripeptide
Cryptographic chain of custody.
- Outer PDA hash
- Inputs hash
- Merkle root
- TEE attestation
- Protocol version
- PDA-V1
- Source
- peptide-md
- Model version
- structure-fm-2026.04
- Candidates emitted
- 3
- Signed
- 2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with
@peptide-md/verifier.Real-world evidence
Cohort-attested outcomes.
Cohorts
7
Participants
219
Mean Δ
+1.71
Δ HRV ms (8-week) · 95% CI [0.38, 3.04]
IPNFT - Not minted
This peptide is not currently represented as an IPNFT. Cohort outcomes feed back into the unminted pool.
Source literature.
Grade B2008 · Gastroenterology
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
Dalmasso G et al.