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Peptide A

Enfuvirtide (Fuzeon)

verifiedBioGate · GREENGrade B
multidrug-resistant HIV-1 infection (FDA approved)
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF
    GEPPPGKPADDAGLV
  • Length≠
    36 aa
    15 aa
  • Molecular weight≠
    4491.88
    1419.55
  • Modifications≠
    acetylated N-terminusamidated C-terminus36-residue HR2-derived
    acetyl-N-terminus
  • Mechanism

    Synthetic peptide derived from HIV-1 gp41 HR2; binds HR1 to block six-helix bundle formation and prevent viral-host membrane fusion.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    3
    4
Outcomes
  • RWE cohorts≠
    4
    5
  • Total participants≠
    293
    270
  • Primary endpoint Δ≠
    +7.27 Δ HRV ms (8-week)
    95% CI [6.62, 7.91]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    91.5%
    β(70.1, 6.5)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    Molecule IPNFT V2
    Solana · 39 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    7.43%
    10.04%
Indications
  • Listed indications≠
    • · multidrug-resistant HIV-1 infection (FDA approved)
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing