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verifiedBioGate · GREENGrade B
Enfuvirtide (Fuzeon)
YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWFSynthetic peptide derived from HIV-1 gp41 HR2; binds HR1 to block six-helix bundle formation and prevent viral-host membrane fusion.
acetylated N-terminusamidated C-terminus36-residue HR2-derived
MW
4491.88
Length
36aa
Posterior
91.5%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · acetylated N-terminus
Cryptographic chain of custody.
- Outer PDA hash
- Inputs hash
- Merkle root
- TEE attestation
- Protocol version
- PDA-V1
- Source
- peptide-md
- Model version
- structure-fm-2026.04
- Candidates emitted
- 3
- Signed
- 2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with
@peptide-md/verifier.Real-world evidence
Cohort-attested outcomes.
Cohorts
4
Participants
293
Mean Δ
+7.27
Δ HRV ms (8-week) · 95% CI [6.62, 7.91]
IPNFT · Molecule IPNFT V2Solana
Enfuvirtide (Fuzeon)
375de5…1a3c5dRoyalty cascade
7.43%
Holders
39
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Source literature.
Grade A2003 · N Engl J Med
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection
Lalezari JP et al.