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Peptide A

Cagrilintide

verifiedBioGate · GREENGrade B
obesity (combination with semaglutide)
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    KCNTATCATNRLANFLVRSSNNLGPVLPPTNVGSNTY
    GEPPPGKPADDAGLV
  • Length≠
    37 aa
    15 aa
  • Molecular weight≠
    3890.40
    1419.55
  • Modifications≠
    disulfide C2-C7γGlu-C18 lipid sidechainamidated C-terminus
    acetyl-N-terminus
  • Mechanism

    Long-acting amylin analog; suppresses appetite and gastric emptying. In Phase 3 as CagriSema combination with semaglutide.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    2
    4
Outcomes
  • RWE cohorts≠
    1
    5
  • Total participants≠
    216
    270
  • Primary endpoint Δ≠
    +2.32 Δ HRV ms (8-week)
    95% CI [0.8, 3.83]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    39.3%
    β(35.1, 54.2)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    Molecule IPNFT V2
    Solana · 115 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    4.07%
    10.04%
Indications
  • Listed indications≠
    • · obesity (combination with semaglutide)
    • · weight management
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing