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verifiedBioGate · GREENGrade B

Cagrilintide

KCNTATCATNRLANFLVRSSNNLGPVLPPTNVGSNTY

Long-acting amylin analog; suppresses appetite and gastric emptying. In Phase 3 as CagriSema combination with semaglutide.

disulfide C2-C7γGlu-C18 lipid sidechainamidated C-terminus
MW
3890.40
Length
37aa
Posterior
39.3%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · disulfide C2-C7
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
2
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
1
Participants
216
Mean Δ
+2.32
Δ HRV ms (8-week) · 95% CI [0.8, 3.83]
IPNFT · Molecule IPNFT V2Solana
Cagrilintide
747c54…20717c
Royalty cascade
4.07%
Holders
115
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Citations

Source literature.

Grade A2021 · Lancet

Once-weekly cagrilintide for weight management in people with overweight and obesity

Lau DCW et al.

PMID 34672969