Grade CRUOverifiedBioGate · GREEN

Circadian & Pineal Support - Epitalon

Longevity/research-use circadian rhythm and pineal gland support in adults > 50

epitalon ↗

Protocol card

Eight audiences, one source of truth.

For clinicians

Dose & cycle

Epitalon 10 mg SC daily × 10 days

Cycle

10 days every 6 months

Duration

12-month observation

For patients

Monitoring endpoints

✓nocturnal melatonin AUC
✓Oura sleep latency
✓HOMA-IR

Contraindications

✕active malignancy
✕uncontrolled hormone-sensitive disease

Jurisdiction gates

US ✓

Research use only

EU ✕

Not approved

Constituent peptides

Provenance, attestations, and structures.

EpitalonverifiedBioGate · GREEN

Structural preview · ESMFold-2 mockdeterministic per sequence

AEDG

Tetrapeptide; in vitro evidence of telomerase activation in somatic cell lines, melatonin rhythm modulation in animal models.

IP economics

Cohort outcomes feed the royalty cascade.

Every revealed OEA from this protocol's cohorts updates the upstream IPNFT's outcome posterior. Holders receive pro-rata royalties from licensing, lab-fee escrow, and approved CRO contracts. Peptide MD does not custody the IPNFT; it indexes it through the Molecule registry.

IPNFT · Molecule IPNFT V2Solana

Epitalon

ce54e2…11c954

Royalty cascade

5.17%

Holders

425

Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.

Citations

Every claim, traceable.

Grade C2003 · Bull Exp Biol Med

Epithalamin and epithalon peptides: telomerase activation in somatic cells

Khavinson VK et al.

PMID 12937360