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verifiedBioGate · GREENGrade B

Vasoactive Intestinal Peptide (VIP)

HSDAVFTDNYTRLRKQMAVKKYLNSILN

28-residue VIP/secretin family neuropeptide; activates VPAC1/VPAC2 for smooth muscle relaxation, vasodilation, and immune modulation.

amidated C-terminus28-residue secretin family
MW
3326.78
Length
28aa
Posterior
82.0%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · amidated C-terminus
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
1
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
3
Participants
294
Mean Δ
+6.47
Δ HRV ms (8-week) · 95% CI [5.87, 7.07]
IPNFT - Not minted

This peptide is not currently represented as an IPNFT. Cohort outcomes feed back into the unminted pool.

Citations

Source literature.

Grade B2001 · Cardiovasc Res

Vasoactive intestinal peptide: cardiovascular effects

Henning RJ, Sawmiller DR.

PMID 16684805