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verifiedBioGate · GREENGrade C

Teduglutide

HGDGSFSDEMNTILDNLAARDFINWLIQTKITD

GLP-2 analog resistant to DPP-4; FDA-approved (Gattex) to promote intestinal mucosal growth and reduce parenteral nutrition need in SBS.

Gly² substitution from native GLP-2
MW
3752.13
Length
33aa
Posterior
12.3%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · Gly² substitution from native GLP-2
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
4
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Citations

Source literature.

Grade A2011 · Gut

Teduglutide reduces need for parenteral support in short-bowel syndrome

Jeppesen PB et al.

PMID 21873748