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verifiedBioGate · GREENGrade C

MOTS-c

MRWQEMGYIFYPRKLR

16-residue peptide encoded in the 12S rRNA of mitochondrial DNA; activates AMPK and improves insulin sensitivity in animal models.

mitochondrial-derived peptide
MW
2174.60
Length
16aa
Posterior
26.2%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · mitochondrial-derived peptide
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
1
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Citations

Source literature.

Grade B2015 · Cell Metab

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis

Lee C et al.

PMID 25738459