← All peptidesPDA-V1 attestation Citations
verifiedBioGate · GREENGrade B
Leuprolide (Lupron)
EHWSYwLRPN-EtGnRH agonist; chronic dosing causes pituitary GnRH receptor desensitization, suppressing LH/FSH and downstream gonadal steroids.
pyroGlu¹D-Leu⁶ethylamide C-terminus
MW
1209.40
Length
13aa
Posterior
87.5%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · pyroGlu¹
Cryptographic chain of custody.
- Outer PDA hash
- Inputs hash
- Merkle root
- TEE attestation
- Protocol version
- PDA-V1
- Source
- peptide-md
- Model version
- structure-fm-2026.04
- Candidates emitted
- 1
- Signed
- 2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with
@peptide-md/verifier.Real-world evidence
Cohort-attested outcomes.
Cohorts
5
Participants
428
Mean Δ
-1.16
Δ HRV ms (8-week) · 95% CI [-1.64, -0.67]
IPNFT · Molecule IPNFT V2Solana
Leuprolide (Lupron)
d59706…aed297Royalty cascade
3.12%
Holders
172
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Source literature.
Grade A1984 · N Engl J Med
Leuprolide versus diethylstilbestrol for metastatic prostate cancer
Leuprolide Study Group.