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warningBioGate · AMBERGrade B

Ghrelin (acyl-ghrelin)

GSSFLSPEHQRVQQRKESKKPPAKLQPR

Endogenous 28-residue peptide from gastric P/D1 cells; acylation at Ser³ enables GHS-R1a binding to drive appetite and GH release.

O-octanoyl @ Ser³endogenous gastric peptide
MW
3370.86
Length
28aa
Posterior
41.8%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · O-octanoyl @ Ser³
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
1
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
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Real-world evidence

Cohort-attested outcomes.

Cohorts
6
Participants
85
Mean Δ
+7.92
Δ HRV ms (8-week) · 95% CI [6.94, 8.9]
IPNFT - Not minted

This peptide is not currently represented as an IPNFT. Cohort outcomes feed back into the unminted pool.

Citations

Source literature.

Grade A1999 · Nature

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Kojima M et al.

PMID 10604470