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verifiedBioGate · GREENGrade B

Dulaglutide (Trulicity)

HGEGTFTSDVSSYLEEQAAKEFIAWLVKGGG

Long-acting GLP-1 receptor agonist fused to Fc; ~5-day half-life via FcRn recycling. Approved for T2D and MACE reduction.

GLP-1 analog fused to IgG4 Fc fragmentweekly SC dosing
MW
59670.00
Length
31aa
Posterior
39.1%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · GLP-1 analog fused to IgG4 Fc fragment
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
2
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
4
Participants
237
Mean Δ
-1.71
Δ HRV ms (8-week) · 95% CI [-2.32, -1.09]
IPNFT · Molecule IPNFT V2Solana
Dulaglutide (Trulicity)
e70813…d9e208
Royalty cascade
10.20%
Holders
450
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Citations

Source literature.

Grade A2014 · Diabetes Care

Efficacy and safety of dulaglutide monotherapy versus metformin in type 2 diabetes (AWARD-3)

Umpierrez G et al.

PMID 25137548