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verifiedBioGate · GREENGrade B

Bivalirudin (Angiomax)

fPRPGGGGNGDFEEIPEEYL

Direct, reversible thrombin inhibitor; binds both catalytic site and exosite I via flexible Gly-linker. Short ~25-min half-life.

D-Phe¹synthetic 20-residue thrombin inhibitor
MW
2180.30
Length
20aa
Posterior
56.5%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · D-Phe¹
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
5
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
6
Participants
65
Mean Δ
+4
Δ HRV ms (8-week) · 95% CI [3.01, 4.98]
IPNFT · Molecule IPNFT V2Solana
Bivalirudin (Angiomax)
8596e3…388296
Royalty cascade
12.72%
Holders
117
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Citations

Source literature.

Grade A2006 · N Engl J Med

Bivalirudin during primary PCI in acute myocardial infarction (HORIZONS-AMI)

Stone GW et al.

PMID 16540615