verifiedBioGate · GREENGrade B

Atrial Natriuretic Peptide (ANP)

SLRRSSCFGGRMDRIGAQSGLGCNSFRY

Cardiac atrial hormone released on stretch; binds NPR-A to increase cGMP, promoting natriuresis and vasodilation. Carperitide (Hanp) approved in Japan.

disulfide C7-C2328-residue cardiac hormone

3080.50

Length

28aa

Posterior

40.1%

Structural preview · ESMFold-2 mockdeterministic per sequence

Backbone preview · disulfide C7-C23

PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation

Protocol version: PDA-V1
Source: peptide-md
Model version: structure-fm-2026.04
Candidates emitted: 4
Signed: 2026-04-21T08:14:33Z

Verifiable in your browser at /verifier with @peptide-md/verifier.

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Real-world evidence

Cohort-attested outcomes.

Cohorts

Participants

427

Mean Δ

-0.87

Δ HRV ms (8-week) · 95% CI [-1.84, 0.1]

IPNFT · Molecule IPNFT V2Solana

Atrial Natriuretic Peptide (ANP)

b32b49…f0b02b

Royalty cascade

9.43%

Holders

237

Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.

Citations

Source literature.

Grade A2009 · Handb Exp Pharmacol

Natriuretic peptides: their structures, receptors, and physiological functions

Potter LR et al.

PMID 19805646