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warningBioGate · AMBERGrade B

Abaloparatide (PTHrP analog, Tymlos)

AVSEHQLLHDKGKSIQDLRRRELLEKLLAKLHTA

PTHrP analog with selective PTH1R RG conformation binding; faster anabolic effect with reduced hypercalcemia vs. teriparatide.

PTHrP-related synthetic 34-residue analog
MW
3961.00
Length
34aa
Posterior
40.8%
Structural preview · ESMFold-2 mockdeterministic per sequence
Backbone preview · PTHrP-related synthetic 34-residue analog
PDA-V1 attestation

Cryptographic chain of custody.

Outer PDA hash
Inputs hash
Merkle root
TEE attestation
Protocol version
PDA-V1
Source
peptide-md
Model version
structure-fm-2026.04
Candidates emitted
2
Signed
2026-04-21T08:14:33Z
Verifiable in your browser at /verifier with @peptide-md/verifier.
Real-world evidence

Cohort-attested outcomes.

Cohorts
5
Participants
83
Mean Δ
+2.46
Δ HRV ms (8-week) · 95% CI [1.39, 3.53]
IPNFT · Molecule IPNFT V2Solana
Abaloparatide (PTHrP analog, Tymlos)
6e324e…806b32
Royalty cascade
3.90%
Holders
267
Royalty cascade routes lab fees, licensing, and OEA-attested cohort revenues back to holders, the cohort treasury, and the originating researchers in a 60 / 25 / 15 split.
Citations

Source literature.

Grade A2016 · JAMA

Effect of Abaloparatide vs Placebo on New Vertebral Fractures (ACTIVE)

Miller PD et al.

PMID 27532316