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Identity
  • Sequence
    MEHFPGP
    GEPPPGKPADDAGLV
  • Length
    7 aa
    15 aa
  • Molecular weight
    813.92
    1419.55
  • Modifications
    intranasal formulationACTH(4-7) analog
    acetyl-N-terminus
  • Mechanism

    Heptapeptide ACTH(4-10) analog; upregulates BDNF and NGF in CNS without HPA-axis activation. Approved in Russia for stroke and cognitive indications.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer
  • Inputs hash
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates
    5
    4
Outcomes
  • RWE cohorts
    none
    5
  • Total participants
    -
    270
  • Primary endpoint Δ
    -
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior
    48.2%
    β(57.9, 62.1)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations
    Grade C0 of 1
    Grade B2 of 2
Economics
  • IPNFT
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade
    -
    10.04%
Indications
  • Listed indications
    • · cognitive performance research
    • · stroke recovery (Russia)
    • · neurotrophic
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing