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Two peptides, one row at a time.

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Peptide A

Semaglutide

warningBioGate · AMBERGrade B
type 2 diabetes
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    HXEGTFTSDVSSYLEGQAAKEFIAWLVRGRG
    GEPPPGKPADDAGLV
  • Length≠
    31 aa
    15 aa
  • Molecular weight≠
    4113.58
    1419.55
  • Modifications≠
    AEEA-AEEA-γGlu-C18 lipid sidechain @ K20Aib substitution @ position 2
    acetyl-N-terminus
  • Mechanism

    GLP-1 receptor agonist with extended half-life (~7 days); stimulates glucose-dependent insulin secretion and central appetite suppression.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate≠
    warningBioGate · AMBER
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    3
    4
Outcomes
  • RWE cohorts
    5
    5
  • Total participants≠
    407
    270
  • Primary endpoint Δ≠
    +6.83 Δ HRV ms (8-week)
    95% CI [6.09, 7.58]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    29.7%
    β(10.8, 25.5)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    Molecule IPNFT V2
    Solana · 18 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    13.88%
    10.04%
Indications
  • Listed indications≠
    • · type 2 diabetes
    • · obesity
    • · cardiovascular risk reduction
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing