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Identity
  • Sequence
    EHWSYGLRPG
    GEPPPGKPADDAGLV
  • Length
    10 aa
    15 aa
  • Molecular weight
    1182.31
    1419.55
  • Modifications
    pyroGlu¹amidated C-terminusnative decapeptide
    acetyl-N-terminus
  • Mechanism

    Native hypothalamic decapeptide; pulsatile dosing stimulates LH/FSH release while continuous dosing causes downregulation.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer
  • Inputs hash
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates
    1
    4
Outcomes
  • RWE cohorts
    7
    5
  • Total participants
    107
    270
  • Primary endpoint Δ
    +3.21 Δ HRV ms (8-week)
    95% CI [2.01, 4.4]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior
    29.4%
    β(18.8, 45.2)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT
    Molecule IPNFT V2
    Solana · 340 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade
    12.13%
    10.04%
Indications
  • Listed indications
    • · pituitary function diagnostic
    • · fertility induction
    • · GnRH research
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing