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Identity
  • Sequence
    EGPWLEEEEEAYGWMDF
    GEPPPGKPADDAGLV
  • Length
    17 aa
    15 aa
  • Molecular weight
    2098.20
    1419.55
  • Modifications
    pyroGlu¹amidated C-terminusTyr¹² sulfated isoform exists
    acetyl-N-terminus
  • Mechanism

    G-cell antral hormone; binds CCK-B (gastrin) receptor on parietal cells to drive acid secretion and ECL histamine release.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer
  • Inputs hash
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates
    4
    4
Outcomes
  • RWE cohorts
    6
    5
  • Total participants
    510
    270
  • Primary endpoint Δ
    +5.09 Δ HRV ms (8-week)
    95% CI [4.36, 5.82]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior
    60.7%
    β(73.5, 47.6)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT
    Molecule IPNFT V2
    Solana · 437 holders
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade
    11.04%
    10.04%
Indications
  • Listed indications
    • · acid secretion research
    • · Zollinger-Ellison diagnostic
    • · GI physiology
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing