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Identity
  • Sequence
    CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP
    GEPPPGKPADDAGLV
  • Length
    32 aa
    15 aa
  • Molecular weight
    3431.85
    1419.55
  • Modifications
    disulfide C1-C7amidated C-terminussalmon-derived 32-residue
    acetyl-N-terminus
  • Mechanism

    Salmon calcitonin (~50× more potent than human); inhibits osteoclast resorption via CTR receptor. Available as IN and SC.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate
    verifiedBioGate · GREEN
    verifiedBioGate · GREEN
  • PDA-V1 outer
  • Inputs hash
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates
    4
    4
Outcomes
  • RWE cohorts
    none
    5
  • Total participants
    -
    270
  • Primary endpoint Δ
    -
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior
    90.3%
    β(76.9, 8.3)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations
    Grade B1 of 1
    Grade B2 of 2
Economics
  • IPNFT
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade
    -
    10.04%
Indications
  • Listed indications
    • · postmenopausal osteoporosis
    • · Paget's disease of bone
    • · hypercalcemia
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing