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Two peptides, one row at a time.

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Peptide A

AOD-9604 (hGH 176-191)

warningBioGate · AMBERGrade B
lipolysis research
Peptide B

BPC-157

verifiedBioGate · GREENGrade B
soft-tissue recovery
Identity
  • Sequence≠
    YLRIVQCRSVEGSCGF
    GEPPPGKPADDAGLV
  • Length≠
    16 aa
    15 aa
  • Molecular weight≠
    1815.13
    1419.55
  • Modifications≠
    disulfide C7-C15tyrosine-extended hGH C-terminal fragment
    acetyl-N-terminus
  • Mechanism

    Modified C-terminal fragment of hGH (residues 176-191); preclinically lipolytic but failed to demonstrate clinical weight loss in Phase 2 trials.

    Pentadecapeptide derived from human gastric juice; modulates VEGF and growth-hormone receptor expression in injured tissue.

Provenance
  • BioGate≠
    warningBioGate · AMBER
    verifiedBioGate · GREEN
  • PDA-V1 outer≠
  • Inputs hash≠
  • Model version
    structure-fm-2026.04
    structure-fm-2026.04
  • PDA candidates≠
    5
    4
Outcomes
  • RWE cohorts≠
    6
    5
  • Total participants≠
    459
    270
  • Primary endpoint Δ≠
    +1.09 Δ HRV ms (8-week)
    95% CI [0.64, 1.54]
    -1.7 Δ HRV ms (8-week)
    95% CI [-2.46, -0.94]
  • LOO posterior≠
    68.7%
    β(51.8, 23.6)
    88.1%
    β(33.8, 4.6)
  • Top-grade citations≠
    Grade C0 of 1
    Grade B2 of 2
Economics
  • IPNFT≠
    unminted
    Molecule IPNFT V2
    Solana · 73 holders
  • Royalty cascade≠
    -
    10.04%
Indications
  • Listed indications≠
    • · lipolysis research
    • · obesity (negative Phase 2 outcome)
    • · soft-tissue recovery
    • · GI mucosal repair
    • · tendon healing